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Faculty

  • Professor of Molecular Biophysics and Biochemistry and of Cell Biology; Director, Yale Center for RNA Science and Medicine

    Research Interests
    • Biochemistry
    • Biophysics
    • Cell Nucleus
    • Cell Biology
    • Molecular Biology
    • RNA Splicing
    • Saccharomyces cerevisiae
    • Schizosaccharomyces
    • Transcription, Genetic
    • Zebrafish
    • Alternative Splicing
    • Genomics
    • Nuclear Cap-Binding Protein Complex
  • Professor of Medicine (Immunology)

    Research Interests
    • Agammaglobulinemia
    • Allergy and Immunology
    • Autistic Disorder
    • DiGeorge Syndrome
    • Multiple Sclerosis
    • Toxicodendron
    • T-Lymphocytes
    • Common Variable Immunodeficiency
    • Exosomes
    • Neuropsychiatry
  • William H. Fleming, M.D. Professor of Molecular Biophysics and Biochemistry and Professor of Genetics and of Therapeutic Radiology

    Research Interests
    • Organelle Biogenesis
    • Genetics
    • Molecular Biology
    • Ribonucleoproteins
    • Radiation Oncology
    • RNA Helicases
    • Genes, rRNA
  • Robert I. Levy Professor of Medicine (Cardiovascular Medicine) and Professor of Immunobiology; Associate Chief, Cardiovascular Medicine, Internal Medicine; Senior Vice Chief for Academic Development, Cardiovascular Medicine

    Research Interests
    • Cardiology
    • Endothelium
    • Immune System
    • Inflammation
    • Macrophages
    • T-Lymphocytes
    • RNA Stability
  • Sterling Professor of Molecular, Cellular, and Developmental Biology and Professor of Molecular Biophysics and Biochemistry; Investigator, Howard Hughes Medical Institute, Molecular, Cellular and Developmental Biology; Chair, Dept Basic Science: Molecular Biophysics & Biochemistry

    Research Interests
    • Bacteria
    • Biochemistry
    • Biology
    • Biotechnology
    • Fungi
    • Genetics, Microbial
    • Microbiology
    • Molecular Biology
    • Computational Biology
    • Genomics
    • Metabolomics
  • Assistant Professor

    Research Interests
    • Autoimmune Diseases
    • Immune System
    • Immunotherapy
    • RNA, Double-Stranded
    • Mass Spectrometry
    • RNA, Circular
  • Associate Professor of Genetics and of Neurosurgery

    Research Interests
    • Biomedical Engineering
    • Cell Transformation, Neoplastic
    • Genetics
    • Immunity
    • Immunotherapy
    • Lymphocytes
    • Neoplasm Metastasis
    • Stem Cells
    • Therapeutics
    • Immunotherapy, Adoptive
    • Genomics
    • Systems Biology
    • Metabolomics
    • Bioengineering
    • Synthetic Biology
    • CRISPR-Cas Systems
  • Waldemar Von Zedtwitz Professor of Genetics and Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology; Deputy Director, Yale Cancer Center

    Research Interests
    • DNA Virus Infections
    • Membrane Lipids
    • Neoplasms
    • Peptides
    • Proteins
    • Tumor Virus Infections
    • Virus Diseases
    • Polyomaviridae
    • Papillomaviridae
  • Harold Hodgkinson Professor of Biomedical Engineering; Professor, Pathology

    Research Interests
    • Hematologic Diseases
    • Immune System Diseases
    • Leukemia
    • Lymphoma
    • Analytical, Diagnostic and Therapeutic Techniques and Equipment
  • Anthony N. Brady Professor of Comparative Medicine and of Pathology and Director of Vascular Biology & Therapeutics Program; Director, Vascular Biology and Therapeutics Program

    Research Interests
    • Pathology
    • Atherosclerosis
  • Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute

    Research Interests
    • Biology
    • Diabetes Mellitus
    • DNA, Recombinant
    • Immune System
    • Immunity
    • Lyme Disease
    • Autoimmunity
    • Gene Expression
    • Gene Transfer Techniques
    • Mice, Knockout
    • Cell Lineage
    • Lyme Neuroborreliosis
  • Albert L Williams Professor of Biomedical Informatics and Professor of Molecular Biophysics & Biochemistry, of Computer Science, and of Statistics & Data Science

    Research Interests
    • Biochemistry
    • Biophysics
    • Computer Simulation
    • DNA
    • Image Processing, Computer-Assisted
    • Medical Informatics
    • Computational Biology
    • Genomics
    • Proteomics
    • Molecular Dynamics Simulation
    • Wearable Electronic Devices
    • Deep Learning
    • Data Science
  • Professor of Molecular Biophysics and Biochemistry

    Research Interests
    • Biochemistry
    • Gene Expression Regulation
    • Molecular Biology
    • RNA Processing, Post-Transcriptional
    • Protein Biosynthesis
    • Genomics
    • Transcriptome
  • Fergus F. Wallace Professor of Genetics

    Research Interests
    • Microscopy
    • Developmental Biology
    • Gene Expression Regulation, Developmental
    • Computational Biology
    • Genomics
    • Systems Biology
    • Autism Spectrum Disorder
    • RNA Recognition Motif
  • Robert E. Hunter Professor of Therapeutic Radiology and Professor of Genetics; Chair, Therapeutic Radiology

    Research Interests
    • DNA Repair
    • Genetics
    • Radiation
    • Gene Targeting
    • Radiation Oncology
    • Recombinational DNA Repair
    • Gene Editing
  • Assistant Professor of Pathology

    Research Interests
    • Amyotrophic Lateral Sclerosis
    • Autopsy
    • Cell Biology
    • Neurons
    • Ribonucleoproteins
    • Neurodegenerative Diseases
    • RNA Transport
    • Frontotemporal Lobar Degeneration
    • TDP-43 Proteinopathies
  • Waldemar Von Zedtwitz Professor of Microbial Pathogenesis

    Research Interests
    • Ecology
    • Biological Evolution
    • Genetics
    • Signal Transduction
    • Infectious Disease Medicine
    • Microbiota
  • Associate Professor of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health

    Research Interests
    • Aedes
    • Arthropod Vectors
    • Chikungunya virus
    • Culex
    • Dengue Virus
    • Disease Outbreaks
    • Epidemiology
    • Genetics, Microbial
    • Molecular Sequence Data
    • RNA Viruses
    • West Nile virus
    • Directed Molecular Evolution
  • Assistant Professor of Neuroscience; Co-Director of Graduate Studies, Interdepartmental Neuroscience Program

    Research Interests
    • Amyotrophic Lateral Sclerosis
    • Neurons
    • RNA
    • Motor Neuron Disease
    • RNA-Binding Proteins
    • Computational Biology
    • Neurodegenerative Diseases
    • Genomics
    • RNA Transport
    • Frontotemporal Dementia
    • High-Throughput Nucleotide Sequencing
  • Arthur H and Isabel Bunker Professor of Medicine (Hematology) and Professor of Pathology; Chief, Section of Hematology; Director, DeLuca Center for Innovation in Hematology Research, Yale Cancer Center; Assistant Medical Director CRSL, Yale Cancer Center; Chief, Translational Hematology

    Research Interests
    • Aging
    • Hematopoiesis
    • Hematopoietic Stem Cells
    • Immunity, Innate
    • Immunotherapy
    • Leukemia
    • Methylation
    • Myelodysplastic Syndromes
    • RNA Processing, Post-Transcriptional
    • RNA Splicing
    • Leukemia, Myelomonocytic, Chronic
    • RNA-Binding Proteins
    • Alternative Splicing
    • Xenograft Model Antitumor Assays
    • Adult Stem Cells
    • Single-Cell Analysis
    • Stress Granules
  • Associate Professor Term; Director of Graduate Studies, Microbiology PhD Program of Biological and Biomedical Sciences

    Research Interests
    • Genetics
    • HIV
    • Immunotherapy
    • Microbiology
    • Host-Pathogen Interactions
    • Transcriptome
    • Epigenetic Repression
  • Eaton Professor of Molecular, Cellular and Developmental Biology and Professor of Ecology and Evolutionary Biology

    Research Interests
    • Ecology
    • Biological Evolution
    • Genetics
    • Human Development
    • Molecular Biology
    • Developmental Biology
    • Arabidopsis
  • Professor of Molecular, Cellular and Developmental Biology

    Research Interests
    • Genetics
    • Glioblastoma
    • Genetic Variation
    • Genomics
    • Systems Biology
    • Gene Regulatory Networks
    • Bioengineering
    • Synthetic Biology
    • Gene Editing
  • Sterling Professor of Immunobiology and Professor of Dermatology and of Molecular, Cellular, and Developmental Biology and of Epidemiology (Microbial Diseases); Investigator, Howard Hughes Medical Institute

    Research Interests
    • Arboviruses
    • Autophagy
    • DNA Viruses
    • Herpes Simplex
    • Immune System
    • Immunity, Cellular
    • Immunity, Innate
    • Influenza, Human
    • Molecular Biology
    • Pneumonia, Viral
    • Pregnancy Complications
    • Proviruses
    • RNA Viruses
    • Sexually Transmitted Diseases
    • Tumor Virus Infections
    • Encephalitis, Viral
    • Central Nervous System Viral Diseases
    • Inflammasomes
  • Boehringer Ingelheim Pharmaceuticals, Inc. Professor of Medicine (Pulmonary); Section Chief, Pulmonary, Critical Care & Sleep Medicine

    Research Interests
    • Emphysema
    • Fibrosis
    • Genetics, Medical
    • Lung Diseases
    • RNA
    • Gene Expression
    • Genomics
    • MicroRNAs
    • Metalloproteases
    • Biomarkers, Pharmacological
  • Anthony N. Brady Professor of Laboratory Medicine and Professor of Pathology; Vice Chair for Research Affairs, Laboratory Medicine; Assoc. Director, Yale Stem Cell Center; Assoc. Director, Transfusion Medicine Service; Medical Director, Clinical Cell Processing Laboratory; Medical Director, Advanced Cell Therapy Laboratory

    Research Interests
    • Cell Biology
    • Hematology
    • Leukemia
    • Pathology
    • Stem Cells
    • Gene Expression
    • Bone Marrow Transplantation
  • Eugene Higgins Professor of Cell Biology, and Professor of Genetics, of Obstetrics, Gynecology & Reproductive Sciences, and of Dermatology; Director, Yale Stem Cell Center

    Research Interests
    • Cell Biology
    • Genetics
    • Gynecology
    • RNA Processing, Post-Transcriptional
    • Stem Cells
    • Embryonic Stem Cells
    • Argonaute Proteins
  • Associate Professor of Genetics

    Research Interests
    • Cell Differentiation
    • Hematologic Diseases
    • Hematopoiesis
    • Neoplasms
    • Cell Lineage
  • Associate Professor Tenure; Director of the Zebrafish Phenotyping Core for Precision Medicine, Internal Medicine and Genetics; Co-Director, Yale Cardiovascular Research Center (YCVRC)

    Research Interests
    • Blood-Brain Barrier
    • Cardiovascular System
    • Neurons
    • Zebrafish
    • MicroRNAs
  • Associate Professor of Medicine (Hematology)

    Research Interests
    • Hematopoiesis
    • Hematopoietic Stem Cells
    • Myelodysplastic Syndromes
    • MicroRNAs
    • Cellular Microenvironment
  • Professor of Genetics; Chair, Genetics

    Research Interests
    • Genetics
    • Germ Cells
    • Stem Cells
    • Developmental Biology
    • Caenorhabditis elegans
    • Genomics
    • Epigenomics
  • Goizueta Foundation Professor of Biomedical Engineering and Professor of Cellular and Molecular Physiology and of Chemical Engineering; Affiliated Faculty, Yale Institute for Global Health; Department Chair, Biomedical Engineering

    Research Interests
    • Cell Communication
    • Drug Discovery
  • Alfred Gilman Professor Emeritus of Pharmacology

    Research Interests
    • Cardiovascular Diseases
    • Cell Membrane Permeability
    • Circulatory and Respiratory Physiological Phenomena
    • Neoplasms
    • Chemicals and Drugs
  • Harvey and Kate Cushing Professor of Neuroscience, and Professor of Comparative Medicine, of Genetics and of Psychiatry; Executive Director, Genome Editing Center

  • Associate Professor Tenure; Director of Graduate Admissions, Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS)

    Research Interests
    • Biochemistry
    • Biophysics
    • Chromatin
    • RNA, Untranslated
  • Assistant Professor of Genetics

    Research Interests
    • Biotechnology
    • Cell Nucleus
    • Chromatin
    • Embryonic and Fetal Development
    • Genetics
    • Molecular Biology
    • Reproduction
    • Epigenetic Repression
  • Sterling Professor Emeritus of Molecular Biophysics and Biochemistry

    Research Interests
    • Amino Acyl-tRNA Synthetases
    • Biochemistry
    • Genetic Code
    • Transfer RNA Aminoacylation
    • Synthetic Biology
  • Sterling Professor of Molecular Biophysics and Biochemistry

    Research Interests
    • Autoantibodies
    • Biochemistry
    • Biophysics
    • Cell Transformation, Viral
    • RNA Processing, Post-Transcriptional
    • Gene Expression
    • Ribonucleoproteins, Small Nuclear
  • Provost and Henry Ford II Professor of Molecular Biophysics and Biochemistry and Professor of Chemistry; Howard Hughes Medical Institute Professor

    Research Interests
    • Biochemistry
    • Biophysics
    • Chemistry
    • Ribosomes
    • Biofuels
    • Endophytes
    • Chemicals and Drugs
    • Technology, Industry, Agriculture
  • Anthony N. Brady Professor of Comparative Medicine and of Pathology; Deputy Chair, Comparative Medicine

    Research Interests
    • Cardiovascular Diseases
    • Inflammation
    • Metabolism
    • Angiogenesis Modulating Agents
    • Atherosclerosis
  • Associate Professor

    Research Interests
    • Asthma
    • Immunity, Cellular
    • Macrophage Activation
    • Neoplasms
    • Respiratory Distress Syndrome
    • Angiogenesis Inhibitors
    • MicroRNAs
    • Vascular Endothelial Growth Factor A
  • John Rodman Paul Professor of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health; Director of Graduate Studies

    Research Interests
    • Parasitic Diseases
    • Tropical Medicine
    • Trypanosomiasis, African
    • Genomics
    • RNA Interference

UConn Health/Jackson Labs Affiliated Faculty

  • Assistant Professor, The Jackson Laboratory

    Research Interests: gene expression regulation in cancer; alternative splicing; breast cancer; ovarian cancer; RNA biology

    My research goal is to elucidate how changes in gene expression regulation contribute to cancer. My lab focuses on characterizing the role of alternative-splicing misregulation in breast and ovarian cancer by using 3D cell culture and PDX models. Our unique expertise in both RNA biology and cancer research allows us to connect these distinct fields, and by combining innovative tools and interdisciplinary approaches, to gain novel insights into the molecular mechanism of gene expression regulation in normal and cancer cells. My research findings should lead to the development of novel biomarkers and promising drugs for cancer therapy.

  • In the Beaudoin lab, we are inspired by these two phenomena of dynamic cellular transitions during development and the role of RNA structure in governing the flow of cellular information. We aim to characterize RNA structure and functions to better understand vertebrate development. To this end, our lab uses the zebrafish and human cell lines as model systems, and we integrate an array of approaches that includes RNA molecular biology, computational biology, high throughput sequencing, genome-engineering, genetics, and developmental biology.

  • Professor, Genetics and Genome Sciences, UConn Health

    Research Interests: expression and function of RNA molecules; noncoding RNA molecules in development, cellular physiology and disease; RNA 2’-O methylation; ribosome maturation and function; mRNA translation; embryonic and induced pluripotent stem cells

  • Professor and Chair, Genetics and Genome Sciences, UConn Health; Endowed Chair, Genomics and Personalized Healthcare, UConn Health; Director, UConn Stem Cell Institute; Associate Director, Institute for Systems Genomics, UConn Health

    Research Interests: alternative splicing regulation; alternative splicing in Drosophila; alternative splicing in human embryonic stem cells; Drosophila modENCODE Project; microRNAs in Planarian regeneration

  • Associate Professor, Genetics and Genome Sciences, UConn Health

    Research Interests: post-transcriptional gene regulation, alternative splicing; alternative polyadenylation; circRNAs; RNA function in neurons

  • Assistant Professor, The Jackson Laboratory

    Investigating mechanisms of drug resistance in hematological malignancies with the main goal to develop new therapeutic strategies and providing a blueprint for clinically relevant biomarkers.